STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (475 aa)    
Predicted Functional Partners:
SDN67289.1
precorrin-8X methylmutase.
 
 0.990
cobQ
Adenosylcobyric acid synthase (glutamine-hydrolysing); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
 0.987
SDO07984.1
Precorrin-4/cobalt-precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 0.963
cobD
Adenosylcobinamide-phosphate synthase; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
 
 0.871
SDN83463.1
Adenosylcobinamide kinase.
 
 
 0.838
cbiD
cobalt-precorrin-5B (C1)-methyltransferase; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.837
SDN46185.1
precorrin-3B C17-methyltransferase.
 
  
 0.835
SDN46224.1
Cobalt-precorrin 5A hydrolase.
 
  
 0.824
SDN46330.1
Precorrin-2 C20-methyltransferase /cobalt-factor II C20-methyltransferase.
 
  
 0.821
SDN49272.1
precorrin-6A/cobalt-precorrin-6A reductase.
 
  
 0.819
Your Current Organism:
Desulfonauticus submarinus
NCBI taxonomy Id: 206665
Other names: CIP 107713, D. submarinus, DSM 15269, Desulfonauticus submarinus Audiffrin et al. 2003, strain 6N
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