STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aroBBifunctional shikimate kinase-3-dehydroquinate synthase protein; AroB; COG family: 3-dehydroquinate synthetase; PFAM_ID: SKI; PFAM_ID: DHQ_synthase; In the N-terminal section; belongs to the shikimate kinase family. (540 aa)    
Predicted Functional Partners:
aroA
3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.
 
 0.999
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
  
 0.997
aroQ
Probable 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family.
 
 0.993
aroE
AroE; COG family: shikimate 5-dehydrogenase; PFAM_ID: Shikimate_DH.
 
 
 0.979
tyrA
TyrA; COG family: prephenate dehydrogenase; PFAM_ID: PDH.
 
  
 0.945
aroG
Phospho-2-keto-3-deoxyheptonate aldolase; DahP synthetase; 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase; AroG; COG family: 3-deoxy-D-arabino-heptulosonate 7-phosphate (DahP) synthase; PFAM_ID: DAHP_synth_1.
  
 
 0.939
aroG2
Phospho-2-dehydro-3-deoxyheptonate aldolase, phe-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP).
  
 
 0.939
der
Probable GTP binding protein; GTPase that plays an essential role in the late steps of ribosome biogenesis; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.
 
  
 0.841
pheA
Probable chorismate mutase (CM); PheA; COG family: prephenate dehydratase; PFAM_ID: PDT; PFAM_ID: ACT.
 
  
 0.834
rpoZ
Probable DNA-directed RNA polymerase omega chain; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
  
 0.821
Your Current Organism:
Bifidobacterium longum
NCBI taxonomy Id: 206672
Other names: B. longum NCC2705, Bifidobacterium longum NCC2705, Bifidobacterium longum str. NCC2705
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