STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
coaEHypothetical protein in upf0038; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (205 aa)    
Predicted Functional Partners:
coaD
Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.
    
 0.984
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.846
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
  
 0.730
rpsA
RpsA; COG family: ribosomal protein S1; PFAM_ID: S1; PFAM_ID: S1; PFAM_ID: S1; PFAM_ID: S1.
  
  
 0.693
pyk
Pyk; COG family: pyruvate kinase; PFAM_ID: PK; PFAM_ID: PK_C; Belongs to the pyruvate kinase family.
 
   
 0.677
BL0989
Widely conserved hypothetical protein with similarity to tellurium resistance protein; TerC; COG family: membrane protein TerC possibly involved in tellurium resistance.
       0.662
folD
Bifunctional methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate.
       0.581
fas
Fas; COG family: 3-oxoacyl-(acyl-carrier-protein) synthase; PFAM_ID: MaoC_dehydratas; PFAM_ID: Acyl_transf; PFAM_ID: ketoacyl-synt; PFAM_ID: ketoacyl-synt_C.
  
  
 0.546
BL0994
COG family: ABC-type Mn/Zn transport system, periplasmic Mn/Zn-binding (lipo)protein (surface adhesin a); PFAM_ID: Lipoprotein_4.
       0.539
aroB
Bifunctional shikimate kinase-3-dehydroquinate synthase protein; AroB; COG family: 3-dehydroquinate synthetase; PFAM_ID: SKI; PFAM_ID: DHQ_synthase; In the N-terminal section; belongs to the shikimate kinase family.
 
  
 0.534
Your Current Organism:
Bifidobacterium longum
NCBI taxonomy Id: 206672
Other names: B. longum NCC2705, Bifidobacterium longum NCC2705, Bifidobacterium longum str. NCC2705
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