node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BL0429 | BL0430 | BL0429 | BL0430 | Possible cobyric acid synthase CobQ; COG family: predicted glutamine amidotransferase. | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | 0.999 |
BL0429 | murG | BL0429 | BL1323 | Possible cobyric acid synthase CobQ; COG family: predicted glutamine amidotransferase. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.901 |
BL0430 | BL0429 | BL0430 | BL0429 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | Possible cobyric acid synthase CobQ; COG family: predicted glutamine amidotransferase. | 0.999 |
BL0430 | ftsI | BL0430 | BL1317 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | Peptidoglycan synthetase; Pbp-3; FtsI or PbpI; COG family: cell division protein FtsI/penicillin-binding protein 2; PFAM_ID: Transpeptidase. | 0.449 |
BL0430 | murC | BL0430 | BL1324 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.441 |
BL0430 | murD | BL0430 | BL1321 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.503 |
BL0430 | murF | BL0430 | BL1319 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.541 |
BL0430 | murG | BL0430 | BL1323 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.950 |
BL0430 | murX | BL0430 | BL1320 | Narrowly conserved hypothetical protein with Mur ligase domain; COG family: UDP-N-acetylmuramyl tripeptide synthase; PFAM_ID: Mur_ligase. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.438 |
ddlA | fstW | BL0345 | BL1322 | D-alanine--D-alanine ligase; Cell wall formation. | Probable FtsW-like protein; FstW; COG family: bacterial cell division membrane protein; PFAM_ID: FTSW_RODA_SPOVE; Belongs to the SEDS family. | 0.663 |
ddlA | ftsI | BL0345 | BL1317 | D-alanine--D-alanine ligase; Cell wall formation. | Peptidoglycan synthetase; Pbp-3; FtsI or PbpI; COG family: cell division protein FtsI/penicillin-binding protein 2; PFAM_ID: Transpeptidase. | 0.583 |
ddlA | ftsZ | BL0345 | BL0118 | D-alanine--D-alanine ligase; Cell wall formation. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.802 |
ddlA | murC | BL0345 | BL1324 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.985 |
ddlA | murD | BL0345 | BL1321 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.863 |
ddlA | murF | BL0345 | BL1319 | D-alanine--D-alanine ligase; Cell wall formation. | UDP-N-acetylmuramoylalanyl-D-glutamyl-2, 6-diaminopimelate--D-alanyl-D-alanyl ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.994 |
ddlA | murG | BL0345 | BL1323 | D-alanine--D-alanine ligase; Cell wall formation. | Undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.947 |
ddlA | murX | BL0345 | BL1320 | D-alanine--D-alanine ligase; Cell wall formation. | phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.778 |
fstW | ddlA | BL1322 | BL0345 | Probable FtsW-like protein; FstW; COG family: bacterial cell division membrane protein; PFAM_ID: FTSW_RODA_SPOVE; Belongs to the SEDS family. | D-alanine--D-alanine ligase; Cell wall formation. | 0.663 |
fstW | ftsI | BL1322 | BL1317 | Probable FtsW-like protein; FstW; COG family: bacterial cell division membrane protein; PFAM_ID: FTSW_RODA_SPOVE; Belongs to the SEDS family. | Peptidoglycan synthetase; Pbp-3; FtsI or PbpI; COG family: cell division protein FtsI/penicillin-binding protein 2; PFAM_ID: Transpeptidase. | 0.982 |
fstW | ftsZ | BL1322 | BL0118 | Probable FtsW-like protein; FstW; COG family: bacterial cell division membrane protein; PFAM_ID: FTSW_RODA_SPOVE; Belongs to the SEDS family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.885 |