STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
icd1Isocitrate dehydrogenase [NADP]; Oxalosuccinate decarboxylase; Idh; NADP+-specific IcdH; Idp; Icd1; COG family: isocitrate dehydrogenases; PFAM_ID: isodh; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (406 aa)    
Predicted Functional Partners:
acn
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.985
gltA2
GltA2; COG family: citrate synthase; PFAM_ID: citrate_synt; Belongs to the citrate synthase family.
  
 
 0.953
gltB
Glutamate synthase [NADPH] large subunit; GltB; COG family: glutamate synthase domain 3; PFAM_ID: Glu_synthase; PFAM_ID: DUF14.
    
 0.934
gdhA
NADP-Gdh; GdhA; COG family: glutamate dehydrogenase/leucine dehydrogenase; PFAM_ID: GLFV_dehydrog_N; PFAM_ID: GLFV_dehydrog; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
   
 0.912
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
  
 0.841
ansB
Aspartase; AnsB; COG family: aspartate ammonia-lyase; PFAM_ID: lyase_1.
     
 0.821
argH
ArgH; COG family: argininosuccinate lyase; PFAM_ID: lyase_1.
     
 0.820
BL0712
Probable aminotransferase Hi0286; COG family: Plp-dependent aminotransferases; PFAM_ID: HTH_3; PFAM_ID: aminotran_1_2.
   
 0.819
BL0783
COG family: Plp-dependent aminotransferases; PFAM_ID: aminotran_1_2.
   
 0.818
nadB
L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.
     
 0.814
Your Current Organism:
Bifidobacterium longum
NCBI taxonomy Id: 206672
Other names: B. longum NCC2705, Bifidobacterium longum NCC2705, Bifidobacterium longum str. NCC2705
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.