node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BL0038 | serC | BL0038 | BL1660 | Conserved protein with hydroxyacid dehydrogenase catalytic domain; COG family: phosphoglycerate dehydrogenase and related dehydrogenases; PFAM_ID: 2-Hacid_DH_C. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.671 |
BL0038 | thrC | BL0038 | BL1036 | Conserved protein with hydroxyacid dehydrogenase catalytic domain; COG family: phosphoglycerate dehydrogenase and related dehydrogenases; PFAM_ID: 2-Hacid_DH_C. | ThrC; COG family: threonine synthase; PFAM_ID: PALP. | 0.426 |
BL0722 | serC | BL0722 | BL1660 | Narrowly conserved hypothetical protein. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.600 |
BL1568 | glyA | BL1568 | BL1035 | Possible 2-hydroxyacid dehydrogenase; COG family: phosphoglycerate dehydrogenase and related dehydrogenases; PFAM_ID: 2-Hacid_DH_C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | 0.409 |
BL1568 | serC | BL1568 | BL1660 | Possible 2-hydroxyacid dehydrogenase; COG family: phosphoglycerate dehydrogenase and related dehydrogenases; PFAM_ID: 2-Hacid_DH_C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.684 |
BL1568 | thrC | BL1568 | BL1036 | Possible 2-hydroxyacid dehydrogenase; COG family: phosphoglycerate dehydrogenase and related dehydrogenases; PFAM_ID: 2-Hacid_DH_C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | ThrC; COG family: threonine synthase; PFAM_ID: PALP. | 0.426 |
BL1659 | serC | BL1659 | BL1660 | Hypothetical protein. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.687 |
fas | glyA | BL1537 | BL1035 | Fas; COG family: 3-oxoacyl-(acyl-carrier-protein) synthase; PFAM_ID: MaoC_dehydratas; PFAM_ID: Acyl_transf; PFAM_ID: ketoacyl-synt; PFAM_ID: ketoacyl-synt_C. | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | 0.827 |
fas | hisC | BL1537 | BL1296 | Fas; COG family: 3-oxoacyl-(acyl-carrier-protein) synthase; PFAM_ID: MaoC_dehydratas; PFAM_ID: Acyl_transf; PFAM_ID: ketoacyl-synt; PFAM_ID: ketoacyl-synt_C. | Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HisC; COG family: histidinol-phosphate aminotransferase/tyrosine aminotransferase; PFAM_ID: aminotran_1_2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.403 |
fas | serC | BL1537 | BL1660 | Fas; COG family: 3-oxoacyl-(acyl-carrier-protein) synthase; PFAM_ID: MaoC_dehydratas; PFAM_ID: Acyl_transf; PFAM_ID: ketoacyl-synt; PFAM_ID: ketoacyl-synt_C. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.637 |
glyA | BL1568 | BL1035 | BL1568 | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | Possible 2-hydroxyacid dehydrogenase; COG family: phosphoglycerate dehydrogenase and related dehydrogenases; PFAM_ID: 2-Hacid_DH_C; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.409 |
glyA | fas | BL1035 | BL1537 | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | Fas; COG family: 3-oxoacyl-(acyl-carrier-protein) synthase; PFAM_ID: MaoC_dehydratas; PFAM_ID: Acyl_transf; PFAM_ID: ketoacyl-synt; PFAM_ID: ketoacyl-synt_C. | 0.827 |
glyA | serA | BL1035 | BL1313 | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.409 |
glyA | serB | BL1035 | BL1792 | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | Probable phosphoserine phosphatase; Psp; O-phosphoserine phosphohydrolase; Pspase; SerB; COG family: phosphoserine phosphatase; PFAM_ID: Hydrolase. | 0.922 |
glyA | serC | BL1035 | BL1660 | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.671 |
glyA | thrC | BL1035 | BL1036 | GlyA; COG family: glycine hydroxymethyltransferase; PFAM_ID: SHMT; PFAM_ID: SHMT. | ThrC; COG family: threonine synthase; PFAM_ID: PALP. | 0.727 |
hisC | fas | BL1296 | BL1537 | Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HisC; COG family: histidinol-phosphate aminotransferase/tyrosine aminotransferase; PFAM_ID: aminotran_1_2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Fas; COG family: 3-oxoacyl-(acyl-carrier-protein) synthase; PFAM_ID: MaoC_dehydratas; PFAM_ID: Acyl_transf; PFAM_ID: ketoacyl-synt; PFAM_ID: ketoacyl-synt_C. | 0.403 |
hisC | serA | BL1296 | BL1313 | Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HisC; COG family: histidinol-phosphate aminotransferase/tyrosine aminotransferase; PFAM_ID: aminotran_1_2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | D-3-phosphoglycerate dehydrogenase; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.436 |
hisC | serB | BL1296 | BL1792 | Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HisC; COG family: histidinol-phosphate aminotransferase/tyrosine aminotransferase; PFAM_ID: aminotran_1_2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Probable phosphoserine phosphatase; Psp; O-phosphoserine phosphohydrolase; Pspase; SerB; COG family: phosphoserine phosphatase; PFAM_ID: Hydrolase. | 0.527 |
hisC | serC | BL1296 | BL1660 | Histidinol-phosphate aminotransferase; Imidazole acetol-phosphate transaminase; HisC; COG family: histidinol-phosphate aminotransferase/tyrosine aminotransferase; PFAM_ID: aminotran_1_2; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Probable phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.642 |