node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acsA_1 | acsA_2 | BG845_00031 | BG845_00061 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.700 |
acsA_1 | acsA_4 | BG845_00031 | BG845_02903 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.732 |
acsA_1 | acsA_5 | BG845_00031 | BG845_03390 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.729 |
acsA_1 | dml_1 | BG845_00031 | BG845_00180 | Acetyl-coenzyme A synthetase. | 2,3-dimethylmalate lyase. | 0.868 |
acsA_1 | glcB | BG845_00031 | BG845_05565 | Acetyl-coenzyme A synthetase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.946 |
acsA_1 | gltA_2 | BG845_00031 | BG845_00193 | Acetyl-coenzyme A synthetase. | Citrate synthase; Belongs to the citrate synthase family. | 0.816 |
acsA_1 | prpB | BG845_00031 | BG845_00194 | Acetyl-coenzyme A synthetase. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 0.868 |
acsA_1 | sucC | BG845_00031 | BG845_02424 | Acetyl-coenzyme A synthetase. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.838 |
acsA_1 | sucD_2 | BG845_00031 | BG845_02425 | Acetyl-coenzyme A synthetase. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.822 |
acsA_2 | acsA_1 | BG845_00061 | BG845_00031 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.700 |
acsA_2 | acsA_4 | BG845_00061 | BG845_02903 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.733 |
acsA_2 | acsA_5 | BG845_00061 | BG845_03390 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.689 |
acsA_2 | dml_1 | BG845_00061 | BG845_00180 | Acetyl-coenzyme A synthetase. | 2,3-dimethylmalate lyase. | 0.868 |
acsA_2 | glcB | BG845_00061 | BG845_05565 | Acetyl-coenzyme A synthetase. | Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. | 0.946 |
acsA_2 | gltA_2 | BG845_00061 | BG845_00193 | Acetyl-coenzyme A synthetase. | Citrate synthase; Belongs to the citrate synthase family. | 0.816 |
acsA_2 | prpB | BG845_00061 | BG845_00194 | Acetyl-coenzyme A synthetase. | Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. | 0.868 |
acsA_2 | sucC | BG845_00061 | BG845_02424 | Acetyl-coenzyme A synthetase. | Succinyl-CoA ligase [ADP-forming] subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.838 |
acsA_2 | sucD_2 | BG845_00061 | BG845_02425 | Acetyl-coenzyme A synthetase. | Succinyl-CoA ligase [ADP-forming] subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.822 |
acsA_4 | acsA_1 | BG845_02903 | BG845_00031 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.732 |
acsA_4 | acsA_2 | BG845_02903 | BG845_00061 | Acetyl-coenzyme A synthetase. | Acetyl-coenzyme A synthetase. | 0.733 |