STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fdhAGlutathione-independent formaldehyde dehydrogenase. (404 aa)    
Predicted Functional Partners:
OSY35613.1
Putative formate dehydrogenase.
 
  
 0.920
adhD_3
Putative alcohol dehydrogenase D.
  
 
0.916
flhA
S-(hydroxymethyl)glutathione dehydrogenase.
  
 
0.914
OSY35242.1
Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily.
  
 
 0.911
thcE_1
NDMA-dependent methanol dehydrogenase.
  
 
 0.910
thcE_2
NDMA-dependent methanol dehydrogenase.
  
 
 0.910
nqo2
NADH-quinone oxidoreductase subunit 2.
    
 0.907
hndC
NADP-reducing hydrogenase subunit HndC.
    
  0.902
OSY35612.1
NADH-dependent formate dehydrogenase delta subunit FdsD.
     
  0.900
amdA_2
Acetamidase.
     
  0.800
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
Server load: low (18%) [HD]