STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ykoU_3Putative ATP-dependent DNA ligase YkoU. (319 aa)    
Predicted Functional Partners:
OSY42028.1
Putative DNA ligase-like protein/MT0965.
  
 0.997
OSY43124.1
Putative DNA ligase-like protein/MT0965.
  
 0.995
LigC_1
Putative DNA ligase-like protein/MT0965.
   
 0.973
OSY41574.1
Putative DNA ligase-like protein/MT0965.
 
  
0.935
ykoV
Putative DNA repair protein YkoV; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family.
 
  
 0.876
LigC_2
Putative DNA ligase-like protein/MT0965.
   
 0.812
lig
Putative DNA ligase-like protein; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair.
   
 0.748
osmF_2
Putative osmoprotectant uptake system substrate-binding protein OsmF precursor.
       0.746
xthA
Exodeoxyribonuclease III.
 
    0.520
fpg2
Putative formamidopyrimidine-DNA glycosylase-like protein; Belongs to the FPG family.
 
   
 0.473
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
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