STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pxpALamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. (254 aa)    
Predicted Functional Partners:
kipI_2
Kinase A inhibitor.
  
 0.965
kipI_3
Kinase A inhibitor.
  
 0.957
rocA
1-pyrroline-5-carboxylate dehydrogenase; Belongs to the aldehyde dehydrogenase family.
   
 
  0.951
kipA_2
KipI antagonist.
  
 0.949
kipA_3
KipI antagonist.
  
 0.942
OSY39857.1
Hypothetical protein; Belongs to the D-glutamate cyclase family.
    0.935
kipA_1
KipI antagonist.
  
 0.919
OSY39855.1
Natural resistance-associated macrophage protein.
  
 0.917
OSY43071.1
LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
  
  
 
0.912
kipI_1
Kinase A inhibitor.
 
  
 0.904
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
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