node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
arnA | fmt_1 | BG845_00606 | BG845_02691 | Bifunctional polymyxin resistance protein ArnA. | Methionyl-tRNA formyltransferase. | 0.940 |
arnA | fmt_2 | BG845_00606 | BG845_03698 | Bifunctional polymyxin resistance protein ArnA. | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.941 |
arnA | folD_2 | BG845_00606 | BG845_03459 | Bifunctional polymyxin resistance protein ArnA. | Bifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.951 |
arnA | gcvT_6 | BG845_00606 | BG845_04739 | Bifunctional polymyxin resistance protein ArnA. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.910 |
arnA | glyA | BG845_00606 | BG845_00388 | Bifunctional polymyxin resistance protein ArnA. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
arnA | glyA2_1 | BG845_00606 | BG845_00041 | Bifunctional polymyxin resistance protein ArnA. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
arnA | glyA2_2 | BG845_00606 | BG845_03841 | Bifunctional polymyxin resistance protein ArnA. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.918 |
arnA | purN | BG845_00606 | BG845_02428 | Bifunctional polymyxin resistance protein ArnA. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.944 |
fmt_1 | arnA | BG845_02691 | BG845_00606 | Methionyl-tRNA formyltransferase. | Bifunctional polymyxin resistance protein ArnA. | 0.940 |
fmt_1 | fmt_2 | BG845_02691 | BG845_03698 | Methionyl-tRNA formyltransferase. | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | 0.923 |
fmt_1 | folD_2 | BG845_02691 | BG845_03459 | Methionyl-tRNA formyltransferase. | Bifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.939 |
fmt_1 | gcvT_6 | BG845_02691 | BG845_04739 | Methionyl-tRNA formyltransferase. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. | 0.922 |
fmt_1 | glyA | BG845_02691 | BG845_00388 | Methionyl-tRNA formyltransferase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
fmt_1 | glyA2_1 | BG845_02691 | BG845_00041 | Methionyl-tRNA formyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
fmt_1 | glyA2_2 | BG845_02691 | BG845_03841 | Methionyl-tRNA formyltransferase. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
fmt_1 | purH | BG845_02691 | BG845_02429 | Methionyl-tRNA formyltransferase. | Bifunctional purine biosynthesis protein PurH. | 0.440 |
fmt_1 | purN | BG845_02691 | BG845_02428 | Methionyl-tRNA formyltransferase. | Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. | 0.950 |
fmt_2 | arnA | BG845_03698 | BG845_00606 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Bifunctional polymyxin resistance protein ArnA. | 0.941 |
fmt_2 | fmt_1 | BG845_03698 | BG845_02691 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Methionyl-tRNA formyltransferase. | 0.923 |
fmt_2 | folD_2 | BG845_03698 | BG845_03459 | Methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. | Bifunctional protein FolD protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.950 |