STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppsA_3Phosphoenolpyruvate synthase. (848 aa)    
Predicted Functional Partners:
ptsI_1
Phosphoenolpyruvate-protein phosphotransferase; Belongs to the PEP-utilizing enzyme family.
    
 0.906
ptsI_2
Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).
    
 0.906
bmr3_2
Multidrug resistance protein 3.
    
 0.814
OSY39265.1
Bacterial regulatory proteins, tetR family.
       0.773
AnsA
L-asparaginase II.
       0.570
kgd
Multifunctional 2-oxoglutarate metabolism enzyme.
  
  
 0.506
pcpB_4
Pentachlorophenol 4-monooxygenase.
  
  
 0.482
yliI
Soluble aldose sugar dehydrogenase YliI precursor.
       0.451
ppc
Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family.
 
   
 0.418
OSY39260.1
16S ribosomal RNA methyltransferase KsgA/Dim1 family protein.
       0.403
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.