STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ilvEBranched-chain-amino-acid aminotransferase. (373 aa)    
Predicted Functional Partners:
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.985
ilvD_1
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.975
ilvD_2
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.975
ilvD_3
Dihydroxy-acid dehydratase; Belongs to the IlvD/Edd family.
  
 0.975
metB
Cystathionine gamma-synthase.
 
 0.936
metC
Cystathionine beta-lyase.
  
 0.927
ldh_1
Leucine dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.920
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
    
 0.920
hom
Homoserine dehydrogenase.
 
 
 0.910
tdcB_2
L-threonine dehydratase catabolic TdcB.
  
 
 0.905
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
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