STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceE_2Pyruvate dehydrogenase E1 component. (767 aa)    
Predicted Functional Partners:
pdhC_2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
 
 0.975
pdhC_1
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.973
pdhC_3
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex.
  
 0.973
lpdC
Dihydrolipoyl dehydrogenase.
  
 
 0.952
lpd_2
Dihydrolipoyl dehydrogenase.
  
 
 0.952
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.932
bkdA_1
3-methyl-2-oxobutanoate dehydrogenase subunit alpha.
    
 0.930
bkdA_2
3-methyl-2-oxobutanoate dehydrogenase subunit alpha.
    
 0.930
cfiB
2-oxoglutarate carboxylase small subunit; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.920
korA
2-oxoglutarate oxidoreductase subunit KorA.
    
 0.919
Your Current Organism:
Pseudonocardia autotrophica
NCBI taxonomy Id: 2074
Other names: ATCC 19727, Amycolata autotrophica, CIP 107114, DSM 535, IFO 12743, IMSNU 20050, JCM 4348, NBRC 12743, NRRL B-11275, Nocardia autotrophica, P. autotrophica, Streptomyces autotrophicus, VKM Ac-941
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