node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0120 | Dde_3581 | Dde_0120 | Dde_3581 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.818 |
Dde_0120 | mnmE | Dde_0120 | Dde_2392 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.853 |
Dde_0120 | rplC | Dde_0120 | Dde_2257 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.841 |
Dde_0120 | rplM | Dde_0120 | Dde_2607 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.826 |
Dde_0120 | rplN | Dde_0120 | Dde_2247 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.794 |
Dde_0120 | rplO | Dde_0120 | Dde_2238 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.799 |
Dde_0120 | rplQ | Dde_0120 | Dde_2230 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | KEGG: das:Daes_2227 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17; PFAM: Ribosomal protein L17. | 0.830 |
Dde_0120 | rplU | Dde_0120 | Dde_2692 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.795 |
Dde_0120 | rplX | Dde_0120 | Dde_2246 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.836 |
Dde_0120 | rsfS | Dde_0120 | Dde_1756 | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.809 |
Dde_3581 | Dde_0120 | Dde_3581 | Dde_0120 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | KEGG: dvm:DvMF_2024 pseudouridine synthase; PFAM: Pseudouridine synthase, RsuA and RluB/C/D/E/F; RNA-binding S4; SMART: RNA-binding S4; Belongs to the pseudouridine synthase RluA family. | 0.818 |
Dde_3581 | mnmE | Dde_3581 | Dde_2392 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.889 |
Dde_3581 | rplC | Dde_3581 | Dde_2257 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.817 |
Dde_3581 | rplM | Dde_3581 | Dde_2607 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.853 |
Dde_3581 | rplN | Dde_3581 | Dde_2247 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. | 0.780 |
Dde_3581 | rplO | Dde_3581 | Dde_2238 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.808 |
Dde_3581 | rplQ | Dde_3581 | Dde_2230 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | KEGG: das:Daes_2227 50S ribosomal protein L17; TIGRFAM: Ribosomal protein L17; PFAM: Ribosomal protein L17. | 0.814 |
Dde_3581 | rplU | Dde_3581 | Dde_2692 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.836 |
Dde_3581 | rplX | Dde_3581 | Dde_2246 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Ribosomal protein L24; One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit. | 0.832 |
Dde_3581 | rsfS | Dde_3581 | Dde_1756 | KEGG: dvu:DVU0042 RNA methyltransferase; TIGRFAM: RNA methyltransferase TrmH, group 3; PFAM: tRNA/rRNA methyltransferase, SpoU; RNA 2-O ribose methyltransferase, substrate binding; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.849 |