node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0217 | aroQ | Dde_0217 | Dde_1952 | PFAM: Peptidase M24, structural domain; Creatinase; KEGG: dvm:DvMF_1929 peptidase M24. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.604 |
Dde_0217 | efp | Dde_0217 | Dde_1953 | PFAM: Peptidase M24, structural domain; Creatinase; KEGG: dvm:DvMF_1929 peptidase M24. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.413 |
Dde_1988 | Dde_3487 | Dde_1988 | Dde_3487 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | 0.407 |
Dde_1988 | aroQ | Dde_1988 | Dde_1952 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.618 |
Dde_1988 | efp | Dde_1988 | Dde_1953 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.458 |
Dde_1988 | rplM | Dde_1988 | Dde_2607 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.947 |
Dde_1988 | tig | Dde_1988 | Dde_2222 | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Trigger factor; Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase; Belongs to the FKBP-type PPIase family. Tig subfamily. | 0.762 |
Dde_3487 | Dde_1988 | Dde_3487 | Dde_1988 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Preprotein translocase, SecG subunit; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.407 |
Dde_3487 | Dde_3488 | Dde_3487 | Dde_3488 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | PFAM: 3-dehydroquinate synthase, prokaryotic-type; KEGG: dvl:Dvul_2476 3-dehydroquinate synthase. | 0.996 |
Dde_3487 | aroC | Dde_3487 | Dde_2726 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.992 |
Dde_3487 | aroE | Dde_3487 | Dde_3564 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.794 |
Dde_3487 | aroQ | Dde_3487 | Dde_1952 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.667 |
Dde_3487 | efp | Dde_3487 | Dde_1953 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Translation elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.781 |
Dde_3488 | Dde_3487 | Dde_3488 | Dde_3487 | PFAM: 3-dehydroquinate synthase, prokaryotic-type; KEGG: dvl:Dvul_2476 3-dehydroquinate synthase. | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | 0.996 |
Dde_3488 | aroC | Dde_3488 | Dde_2726 | PFAM: 3-dehydroquinate synthase, prokaryotic-type; KEGG: dvl:Dvul_2476 3-dehydroquinate synthase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.414 |
Dde_3488 | aroQ | Dde_3488 | Dde_1952 | PFAM: 3-dehydroquinate synthase, prokaryotic-type; KEGG: dvl:Dvul_2476 3-dehydroquinate synthase. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.900 |
aroC | Dde_3487 | Dde_2726 | Dde_3487 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | 0.992 |
aroC | Dde_3488 | Dde_2726 | Dde_3488 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | PFAM: 3-dehydroquinate synthase, prokaryotic-type; KEGG: dvl:Dvul_2476 3-dehydroquinate synthase. | 0.414 |
aroC | aroE | Dde_2726 | Dde_3564 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.967 |
aroC | aroQ | Dde_2726 | Dde_1952 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.610 |