STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dde_2013Protease Do; SMART: PDZ/DHR/GLGF; TIGRFAM: Peptidase S1C, Do; KEGG: dvl:Dvul_1611 protease Do; PFAM: Peptidase S1/S6, chymotrypsin/Hap; PDZ/DHR/GLGF; Belongs to the peptidase S1C family. (480 aa)    
Predicted Functional Partners:
Dde_1941
KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like.
  
  
 0.652
Dde_1285
Response regulator receiver protein; KEGG: jan:Jann_2988 histidine kinase; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
  
  
 0.609
Dde_2012
KEGG: bja:bll4284 acetyl hydrolace.
 
  
 0.609
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
 
    0.606
glpK
Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.603
Dde_0544
KEGG: dsa:Desal_2870 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker [...]
  
  
 0.597
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
 
 
 
 0.540
Dde_3224
KEGG: dvm:DvMF_1801 phage shock protein C, PspC; TIGRFAM: Phage shock protein C; PFAM: PspC.
  
  
 0.519
rsfS
Iojap-like protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
   0.511
rplT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
  
 
 
 0.504
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
Server load: low (24%) [HD]