STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dde_2277Radical SAM domain protein; KEGG: dsa:Desal_0368 biotin synthase; PFAM: Radical SAM; SMART: Elongator protein 3/MiaB/NifB. (337 aa)    
Predicted Functional Partners:
Dde_2276
KEGG: dsa:Desal_1339 small GTP-binding protein; TIGRFAM: Small GTP-binding protein; PFAM: GTP-binding protein, HSR1-related.
   
 0.991
bioD
Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring.
  
 
 0.982
birA
biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family.
  
 
 0.957
Dde_2082
KEGG: dvm:DvMF_0418 biotin/acetyl-CoA-carboxylase ligase; TIGRFAM: Biotin--acetyl-CoA-carboxylase ligase; PFAM: Biotin/lipoate A/B protein ligase.
  
 
 0.919
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
     
  0.900
Dde_2279
KEGG: das:Daes_0597 transcriptional regulator.
 
  
 0.882
Dde_2281
TIGRFAM: Iron hydrogenase, subset; KEGG: das:Daes_0599 hydrogenase, Fe-only; PFAM: Iron hydrogenase, large subunit, C-terminal; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
  
 0.864
Dde_0475
Fe-only hydrogenase, large & small subunits, cytoplasmic; SMART: Iron hydrogenase, small subunit-like; TIGRFAM: Iron hydrogenase, subset; KEGG: dps:DP0479 Fe-center hydrogenase, large subunit; PFAM: Iron hydrogenase, large subunit, C-terminal; Iron hydrogenase, small subunit-like; 4Fe-4S ferredoxin, iron-sulphur binding, subgroup.
 
  
 0.826
Dde_2280
KEGG: das:Daes_0598 iron hydrogenase small subunit; PFAM: Iron hydrogenase, small subunit-like; SMART: Iron hydrogenase, small subunit-like.
 
   
 0.818
Dde_1148
Hypothetical protein; KEGG: afn:Acfer_0225 biotin and thiamin synthesis associated.
 
   
 0.796
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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