node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0054 | Dde_3487 | Dde_0054 | Dde_3487 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | 0.727 |
Dde_0054 | argB | Dde_0054 | Dde_2015 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.476 |
Dde_0054 | argC | Dde_0054 | Dde_3455 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.426 |
Dde_0054 | proA | Dde_0054 | Dde_1633 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.948 |
Dde_0054 | proB | Dde_0054 | Dde_2689 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.950 |
Dde_0054 | proC | Dde_0054 | Dde_1440 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.960 |
Dde_0054 | ribBA | Dde_0054 | Dde_2436 | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.630 |
Dde_2688 | obg | Dde_2688 | Dde_2690 | TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: dvl:Dvul_2054 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | GTPase obg; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.715 |
Dde_2688 | proB | Dde_2688 | Dde_2689 | TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: dvl:Dvul_2054 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.689 |
Dde_2688 | ribBA | Dde_2688 | Dde_2436 | TIGRFAM: Phosphomethylpyrimidine kinase type-2; KEGG: dvl:Dvul_2054 phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.461 |
Dde_3487 | Dde_0054 | Dde_3487 | Dde_0054 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.727 |
Dde_3487 | argB | Dde_3487 | Dde_2015 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | 0.570 |
Dde_3487 | argC | Dde_3487 | Dde_3455 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. | 0.675 |
Dde_3487 | proA | Dde_3487 | Dde_1633 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.679 |
Dde_3487 | proB | Dde_3487 | Dde_2689 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.608 |
Dde_3487 | proC | Dde_3487 | Dde_1440 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.403 |
Dde_3487 | ribBA | Dde_3487 | Dde_2436 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.636 |
Dde_3487 | rplU | Dde_3487 | Dde_2692 | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.544 |
argB | Dde_0054 | Dde_2015 | Dde_0054 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | Proline dehydrogenase / 1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. | 0.476 |
argB | Dde_3487 | Dde_2015 | Dde_3487 | Acetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. | KEGG: dvm:DvMF_1749 prephenate dehydratase; PFAM: Prephenate dehydratase; Amino acid-binding ACT; Chorismate mutase, type II; SMART: Chorismate mutase. | 0.570 |