Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Dde_3003KEGG: dvm:DvMF_1461 two component, sigma54 specific, transcriptional regulator, fis family; PFAM: RNA polymerase sigma factor 54, interaction; Signal transduction response regulator, receiver region; Helix-turn-helix, Fis-type; SMART: Signal transduction response regulator, receiver region; ATPase, AAA+ type, core. (465 aa)    
Predicted Functional Partners:
Dde_3000
Multi-sensor signal transduction histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; HAMP linker domain; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dvm:DvMF_1458 multi-sensor signal transduction histidine kinase; SMART: ATP-binding region, ATPase-like; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif.
 
 0.990
Dde_3002
Putative PAS/PAC sensor protein; TIGRFAM: PAS; HDIG; PFAM: Metal-dependent phosphohydrolase, HD region, subdomain; Signal transduction response regulator, receiver region; PAS fold-4; KEGG: dvl:Dvul_0434 PAS/PAC sensor protein; SMART: Signal transduction response regulator, receiver region; PAS; Metal-dependent phosphohydrolase, HD region.
  
 
 0.823
Dde_3001
PFAM: Domain of unknown function DUF1731, C-terminal; NAD-dependent epimerase/dehydratase; KEGG: dvl:Dvul_0435 hypothetical protein.
       0.793
Dde_1771
RNA polymerase, sigma 54 subunit, RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.696
Dde_2999
KEGG: dvm:DvMF_1457 hypothetical protein.
       0.696
Dde_3005
PFAM: Ion transport; KEGG: pca:Pcar_0515 ion transport protein.
       0.644
gpmA
Phosphoglycerate mutase 1 family; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.
  
    0.642
Dde_3038
TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; PAS fold; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dal:Dalk_0185 signal transduction histidine kinase, nitrogen specific, NtrB; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS; PAC motif.
 
 
 0.517
Dde_1015
Histidine kinase; KEGG: met:M446_5170 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
 
 
 0.510
Dde_1684
Signal transduction histidine kinase, nitrogen specific, NtrB; KEGG: dvm:DvMF_0213 multi-sensor signal transduction histidine kinase; PFAM: ATP-binding region, ATPase-like; PAS fold-4; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS.
 
 
 0.507
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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