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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dde_3206TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS fold-4; KEGG: das:Daes_2438 PAS sensor protein; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; PAS. (374 aa)    
Predicted Functional Partners:
Dde_1941
KEGG: mgm:Mmc1_3271 PAS/PAC sensor hybrid histidine kinase; PFAM: Signal transduction response regulator, receiver region; ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; SMART: Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; ATP-binding region, ATPase-like.
 
 
 0.992
Dde_0544
KEGG: dsa:Desal_2870 Hpt sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker [...]
 
 
 0.981
Dde_0370
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; PAS fold; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: dvm:DvMF_2273 PAS/PAC sensor hybrid histidine kinase; SMART: Signal transduction response regulator, receiver region; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain; ATP-binding region, ATPase-like.
 
 
 0.980
Dde_1697
Multi-sensor hybrid histidine kinase; KEGG: dma:DMR_25470 two-component hybrid sensor and regulator; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; Signal transduction histidine kinase, phosphotransfer (Hpt) region; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoaccep [...]
 
 
 0.980
Dde_1015
Histidine kinase; KEGG: met:M446_5170 PAS/PAC sensor hybrid histidine kinase; PFAM: ATP-binding region, ATPase-like; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region.
 
 
 0.972
Dde_1285
Response regulator receiver protein; KEGG: jan:Jann_2988 histidine kinase; PFAM: Signal transduction response regulator, receiver region; SMART: Signal transduction response regulator, receiver region.
 
 
 0.961
Dde_1360
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS fold-4; Signal transduction response regulator, receiver region; KEGG: dvu:DVU2412 sensory box histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; GAF; PAS; Signal transduction response regulator, receiver region.
 
 
 0.954
Dde_1686
Hpt domain protein; PFAM: Signal transduction histidine kinase, phosphotransfer (Hpt) region; KEGG: dvm:DvMF_0217 Hpt protein.
  
 
 0.953
Dde_2769
Multi-sensor hybrid histidine kinase; TIGRFAM: PAS; PFAM: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; PAS fold-3; HAMP linker domain; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; KEGG: sfu:Sfum_2304 multi-sensor hybrid histidine kinase; SMART: ATP-binding region, ATPase-like; Signal transduction response regulator, receiver region; PAS; PAC motif; Signal transduction histidine kinase, subgroup 1, dimerisation/phosphoacceptor region; HAMP linker domain.
 
 
 0.951
Dde_2387
KEGG: dvm:DvMF_0882 two component transcriptional regulator, winged helix family; PFAM: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal; SMART: Signal transduction response regulator, receiver region; Signal transduction response regulator, C-terminal.
 
 
 0.928
Your Current Organism:
Desulfovibrio alaskensis
NCBI taxonomy Id: 207559
Other names: D. alaskensis G20, Desulfovibrio alaskensis G20, Desulfovibrio alaskensis str. G20, Desulfovibrio alaskensis strain G20, Desulfovibrio desulfuricans subsp. desulfuricans str. G20
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