node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Dde_0001 | Dde_3749 | Dde_0001 | Dde_3749 | Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | KEGG: epy:EpC_06760 ATPase domain protein. | 0.499 |
Dde_0001 | birA | Dde_0001 | Dde_2654 | Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.449 |
Dde_0001 | dnaA | Dde_0001 | Dde_2320 | Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.914 |
Dde_0001 | topA | Dde_0001 | Dde_0106 | Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.550 |
Dde_0029 | Dde_3749 | Dde_0029 | Dde_3749 | TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: dvm:DvMF_2045 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family. | KEGG: epy:EpC_06760 ATPase domain protein. | 0.816 |
Dde_0029 | dnaA | Dde_0029 | Dde_2320 | TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: dvm:DvMF_2045 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.526 |
Dde_0029 | ftsZ | Dde_0029 | Dde_1047 | TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: dvm:DvMF_2045 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.610 |
Dde_0029 | topA | Dde_0029 | Dde_0106 | TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: dvm:DvMF_2045 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.625 |
Dde_1542 | Dde_3749 | Dde_1542 | Dde_3749 | KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. | KEGG: epy:EpC_06760 ATPase domain protein. | 0.533 |
Dde_1542 | birA | Dde_1542 | Dde_2654 | KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.717 |
Dde_1542 | ftsZ | Dde_1542 | Dde_1047 | KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. | Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. | 0.550 |
Dde_1542 | guaB | Dde_1542 | Dde_1471 | KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.585 |
Dde_1542 | topA | Dde_1542 | Dde_0106 | KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.551 |
Dde_2584 | Dde_3749 | Dde_2584 | Dde_3749 | ABC-type transporter, periplasmic subunit family 3; PFAM: Extracellular solute-binding protein, family 3; KEGG: swd:Swoo_1419 hypothetical protein. | KEGG: epy:EpC_06760 ATPase domain protein. | 0.463 |
Dde_3749 | Dde_0001 | Dde_3749 | Dde_0001 | KEGG: epy:EpC_06760 ATPase domain protein. | Chromosomal replication initiator DnaA domain-containing protein; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.499 |
Dde_3749 | Dde_0029 | Dde_3749 | Dde_0029 | KEGG: epy:EpC_06760 ATPase domain protein. | TIGRFAM: ParB-like partition protein; PFAM: ParB-like nuclease; KEGG: dvm:DvMF_2045 ParB-like partition protein; SMART: ParB-like nuclease; Belongs to the ParB family. | 0.816 |
Dde_3749 | Dde_1542 | Dde_3749 | Dde_1542 | KEGG: epy:EpC_06760 ATPase domain protein. | KEGG: dvm:DvMF_0816 acetyl-CoA carboxylase; PFAM: Acetyl-CoA carboxylase, alpha subunit, conserved region. | 0.533 |
Dde_3749 | Dde_2584 | Dde_3749 | Dde_2584 | KEGG: epy:EpC_06760 ATPase domain protein. | ABC-type transporter, periplasmic subunit family 3; PFAM: Extracellular solute-binding protein, family 3; KEGG: swd:Swoo_1419 hypothetical protein. | 0.463 |
Dde_3749 | birA | Dde_3749 | Dde_2654 | KEGG: epy:EpC_06760 ATPase domain protein. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.522 |
Dde_3749 | dnaA | Dde_3749 | Dde_2320 | KEGG: epy:EpC_06760 ATPase domain protein. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.499 |