node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAT11597.1 | EAT12971.1 | RED65_07909 | RED65_14782 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.900 |
EAT11597.1 | EAT12972.1 | RED65_07909 | RED65_14787 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | Nicotinamide nucleotide transhydrogenase, subunit alpha; COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.900 |
EAT11597.1 | EAT12973.1 | RED65_07909 | RED65_14792 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.900 |
EAT11597.1 | EAT13296.1 | RED65_07909 | RED65_01010 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | Putative sirtuin; COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.921 |
EAT11597.1 | MazG | RED65_07909 | RED65_03860 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | COG1694 Predicted pyrophosphatase. | 0.910 |
EAT11597.1 | nadD | RED65_07909 | RED65_08124 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.904 |
EAT11597.1 | nadE | RED65_07909 | RED65_05104 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.911 |
EAT11597.1 | ppnK | RED65_07909 | RED65_05494 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.902 |
EAT11597.1 | sthA | RED65_07909 | RED65_00995 | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.902 |
EAT12971.1 | EAT11597.1 | RED65_14782 | RED65_07909 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | 0.900 |
EAT12971.1 | EAT12972.1 | RED65_14782 | RED65_14787 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinamide nucleotide transhydrogenase, subunit alpha; COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |
EAT12971.1 | EAT12973.1 | RED65_14782 | RED65_14792 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | COG3288 NAD/NADP transhydrogenase alpha subunit. | 0.999 |
EAT12971.1 | EAT13296.1 | RED65_14782 | RED65_01010 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Putative sirtuin; COG0846 NAD-dependent protein deacetylases, SIR2 family. | 0.901 |
EAT12971.1 | MazG | RED65_14782 | RED65_03860 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | COG1694 Predicted pyrophosphatase. | 0.901 |
EAT12971.1 | nadD | RED65_14782 | RED65_08124 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.902 |
EAT12971.1 | nadE | RED65_14782 | RED65_05104 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.937 |
EAT12971.1 | ppnK | RED65_14782 | RED65_05494 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.906 |
EAT12971.1 | sthA | RED65_14782 | RED65_00995 | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | Soluble pyridine nucleotide transhydrogenase; Conversion of NADPH, generated by peripheral catabolic pathways, to NADH, which can enter the respiratory chain for energy generation; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. | 0.908 |
EAT12972.1 | EAT11597.1 | RED65_14787 | RED65_07909 | Nicotinamide nucleotide transhydrogenase, subunit alpha; COG3288 NAD/NADP transhydrogenase alpha subunit. | NUDIX hydrolase; COG1051 ADP-ribose pyrophosphatase. | 0.900 |
EAT12972.1 | EAT12971.1 | RED65_14787 | RED65_14782 | Nicotinamide nucleotide transhydrogenase, subunit alpha; COG3288 NAD/NADP transhydrogenase alpha subunit. | H+-translocating transhydrogenase subunit beta; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family. | 0.999 |