node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAT13305.1 | RibD | RED65_01055 | RED65_16081 | ATP-grasp domain-containing protein; COG0825 Acetyl-CoA carboxylase alpha subunit. | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.839 |
EAT13305.1 | mnmA | RED65_01055 | RED65_01490 | ATP-grasp domain-containing protein; COG0825 Acetyl-CoA carboxylase alpha subunit. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.793 |
EAT13305.1 | nudJ | RED65_01055 | RED65_01495 | ATP-grasp domain-containing protein; COG0825 Acetyl-CoA carboxylase alpha subunit. | Putative Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.498 |
EAT13394.1 | hflD | RED65_01500 | RED65_01485 | Pseudouridine synthase, Rsu; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | COG2915 Uncharacterized protein involved in purine metabolism. | 0.818 |
EAT13394.1 | mnmA | RED65_01500 | RED65_01490 | Pseudouridine synthase, Rsu; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.826 |
EAT13394.1 | nudJ | RED65_01500 | RED65_01495 | Pseudouridine synthase, Rsu; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | Putative Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.924 |
EAT13467.1 | mnmA | RED65_08754 | RED65_01490 | DsrC-like protein; Part of a sulfur-relay system. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.937 |
PurB | hflD | RED65_01475 | RED65_01485 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | COG2915 Uncharacterized protein involved in purine metabolism. | 0.764 |
PurB | metG | RED65_01475 | RED65_08939 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | Methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. | 0.550 |
PurB | mnmA | RED65_01475 | RED65_01490 | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.855 |
RibD | EAT13305.1 | RED65_16081 | RED65_01055 | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | ATP-grasp domain-containing protein; COG0825 Acetyl-CoA carboxylase alpha subunit. | 0.839 |
RibD | RibF | RED65_16081 | RED65_07969 | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Hypothetical protein; COG0196 FAD synthase; Belongs to the ribF family. | 0.764 |
RibD | mnmA | RED65_16081 | RED65_01490 | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.590 |
RibD | mnmE | RED65_16081 | RED65_08534 | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | tRNA modification GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.476 |
RibF | RibD | RED65_07969 | RED65_16081 | Hypothetical protein; COG0196 FAD synthase; Belongs to the ribF family. | Riboflavin-specific deaminase/reductase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.764 |
RibF | mnmA | RED65_07969 | RED65_01490 | Hypothetical protein; COG0196 FAD synthase; Belongs to the ribF family. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.686 |
hflD | EAT13394.1 | RED65_01485 | RED65_01500 | COG2915 Uncharacterized protein involved in purine metabolism. | Pseudouridine synthase, Rsu; COG1187 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases; Belongs to the pseudouridine synthase RsuA family. | 0.818 |
hflD | PurB | RED65_01485 | RED65_01475 | COG2915 Uncharacterized protein involved in purine metabolism. | COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.764 |
hflD | mnmA | RED65_01485 | RED65_01490 | COG2915 Uncharacterized protein involved in purine metabolism. | tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. | 0.983 |
hflD | nudJ | RED65_01485 | RED65_01495 | COG2915 Uncharacterized protein involved in purine metabolism. | Putative Nudix hydrolase; COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Belongs to the Nudix hydrolase family. NudJ subfamily. | 0.818 |