EAT10865.1 protein (Bermanella marisrubri) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

EAT10865.1

TraH. (475 aa)

Predicted Functional Partners:

EAT10866.1

0.954

EAT10863.1

0.951

EAT10864.1

0.951

TraU

0.911

EAT10859.1

0.897

EAT10860.1

0.897

EAT10855.1

0.877

TraC

0.877

EAT10867.1

0.773

EAT10862.1

0.603

Your Current Organism:

Bermanella marisrubri

NCBI taxonomy Id: 207949
Other names: B. marisrubri, Bermanella marisrubri Pinhassi et al. 2009, CCUG 52064, CECT 7074, Oceanobacter sp. RED65, strain RED65

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EAT10855.1	EAT10859.1	RED65_01913	RED65_01933	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	0.913
EAT10855.1	EAT10860.1	RED65_01913	RED65_01938	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	TraW.	0.916
EAT10855.1	EAT10862.1	RED65_01913	RED65_01948	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	Hypothetical protein; COG1210 UDP-glucose pyrophosphorylase.	0.665
EAT10855.1	EAT10863.1	RED65_01913	RED65_01953	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	Hypothetical protein.	0.877
EAT10855.1	EAT10864.1	RED65_01913	RED65_01958	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins.	0.877
EAT10855.1	EAT10865.1	RED65_01913	RED65_01963	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	TraH.	0.877
EAT10855.1	EAT10866.1	RED65_01913	RED65_01968	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	TraG; COG0840 Methyl-accepting chemotaxis protein.	0.877
EAT10855.1	EAT10867.1	RED65_01913	RED65_01973	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	Hypothetical protein.	0.414
EAT10855.1	TraC	RED65_01913	RED65_01923	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	ATPase; COG3451 Type IV secretory pathway, VirB4 components.	0.954
EAT10855.1	TraU	RED65_01913	RED65_01943	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	TraU.	0.916
EAT10859.1	EAT10855.1	RED65_01933	RED65_01913	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	TraB pilus assembly; COG0419 ATPase involved in DNA repair.	0.913
EAT10859.1	EAT10860.1	RED65_01933	RED65_01938	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	TraW.	0.950
EAT10859.1	EAT10862.1	RED65_01933	RED65_01948	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	Hypothetical protein; COG1210 UDP-glucose pyrophosphorylase.	0.794
EAT10859.1	EAT10863.1	RED65_01933	RED65_01953	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	Hypothetical protein.	0.895
EAT10859.1	EAT10864.1	RED65_01933	RED65_01958	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	Hypothetical protein; COG0526 Thiol-disulfide isomerase and thioredoxins.	0.896
EAT10859.1	EAT10865.1	RED65_01933	RED65_01963	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	TraH.	0.897
EAT10859.1	EAT10866.1	RED65_01933	RED65_01968	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	TraG; COG0840 Methyl-accepting chemotaxis protein.	0.898
EAT10859.1	EAT10867.1	RED65_01933	RED65_01973	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	Hypothetical protein.	0.519
EAT10859.1	TraC	RED65_01933	RED65_01923	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	ATPase; COG3451 Type IV secretory pathway, VirB4 components.	0.920
EAT10859.1	TraU	RED65_01933	RED65_01943	Type IV secretory pathway protease TraF-like protein; COG0681 Signal peptidase I.	TraU.	0.950

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

27

average node degree:

4.91

avg. local clustering coefficient:

0.842

expected number of edges:

13

PPI enrichment p-value:

0.000552

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006810

Transport

11 of 466

0.86

0.91

4.39e-07

GO:0055085

Transmembrane transport

9 of 414

0.82

0.76

8.29e-05

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005215

Transporter activity

10 of 391

0.89

0.93

3.12e-06

GO:0005524

ATP binding

8 of 337

0.86

0.74

0.00043

GO:0022857

Transmembrane transporter activity

8 of 386

0.8

0.68

0.00043

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005886

Plasma membrane

11 of 563

0.78

0.79

3.96e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4556

MacB, ATP-binding domain, and FtsX-like permease family

10 of 18

2.23

7.36

2.04e-18

CL:4558

FtsX-like permease family, and ABC transporter, lipoprotein release, LolD-like

8 of 13

2.27

6.22

1.48e-14

CL:4561

FtsX-like permease family

5 of 6

2.41

4.15

6.10e-09

CL:4336

ABC transporters, and Metal ion transmembrane transporter activity

11 of 166

1.31

2.28

9.04e-13

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map02010

ABC transporters

10 of 189

1.21

1.8

4.84e-10

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0098796

Membrane protein complex

4 of 72

1.23

0.82

0.0086

GOCC:0016020

Membrane

11 of 580

0.76

1.09e-06

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0997

Cell inner membrane

5 of 6

2.41

4.03

1.08e-08

KW-0046

Antibiotic resistance

5 of 9

2.23

3.79

1.56e-08

KW-1278

Translocase

5 of 17

1.95

3.08

1.21e-07

KW-0067

ATP-binding

10 of 271

1.05

1.34

1.32e-08

KW-1003

Cell membrane

6 of 182

1.0

0.91

0.00031

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF12704

MacB-like periplasmic core domain

6 of 7

2.42

4.85

1.81e-10

PF02687

FtsX-like permease family

6 of 9

2.31

4.63

2.64e-10

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR017911

MacB, ATP-binding domain

10 of 10

2.48

8.93

4.91e-20

IPR025857

MacB-like periplasmic core domain

6 of 7

2.42

4.97

9.66e-11

IPR003838

ABC3 transporter permease protein domain

6 of 9

2.31

4.65

2.34e-10

IPR003439

ABC transporter-like, ATP-binding domain

10 of 82

1.57

3.26

9.39e-13

IPR017871

ABC transporter-like, conserved site

9 of 70

1.59

3.15

2.22e-11

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00382

ATPases associated with a variety of cellular activities

10 of 105

1.46

2.83

1.64e-12

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (18%) [HD]

Permalink

Network

Neighborhood

Textmining

Cooccurrence

Experiments

Fusion

Databases

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About