STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAT10776.12-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (299 aa)    
Predicted Functional Partners:
EAT12355.1
2-dehydropantoate 2-reductase; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
  
  
  0.969
panB
3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family.
  
 0.961
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.959
EAT13915.1
2OG-Fe(II) oxygenase superfamily protein; COG3145 Alkylated DNA repair protein.
   
    0.616
EAT10775.1
Probable two-component sensor; COG0642 Signal transduction histidine kinase.
       0.585
EAT10777.1
Hypothetical protein.
       0.539
EAT10779.1
Muropeptide MFS uptake transporter AmpG; COG0477 Permeases of the major facilitator superfamily.
       0.500
EAT10778.1
COG1666 Uncharacterized protein conserved in bacteria; Belongs to the UPF0234 family.
       0.470
birA
Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.427
nadE
NAD synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
  
  
 0.422
Your Current Organism:
Bermanella marisrubri
NCBI taxonomy Id: 207949
Other names: B. marisrubri, Bermanella marisrubri Pinhassi et al. 2009, CCUG 52064, CECT 7074, Oceanobacter sp. RED65, strain RED65
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