STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAT12777.1COG0735 Fe2+/Zn2+ uptake regulation proteins; Belongs to the Fur family. (163 aa)    
Predicted Functional Partners:
znuC
Zinc ABC transporter, ATP-binding protein; Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system. Belongs to the ABC transporter superfamily. Zinc importer (TC 3.A.1.15.5) family.
  
  
 0.818
rpoA
DNA-directed RNA polymerase alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
   0.759
birA
Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
     
 0.536
ZnuB
High-affinity zinc uptake system membrane protein ZnuB; COG1108 ABC-type Mn2+/Zn2+ transport systems, permease components.
  
  
 0.530
GltB
COG0067 Glutamate synthase domain 1.
     
 0.502
EAT10803.1
Peroxidase; COG0450 Peroxiredoxin.
  
  
 0.500
EAT13785.1
Antioxidant, AhpC/Tsa family protein; COG0450 Peroxiredoxin.
  
  
 0.500
AhpC
Alkyl hydroperoxide reductase c22 protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.
  
  
 0.500
EAT13067.1
COG1773 Rubredoxin.
  
  
 0.496
EAT11257.1
Zinc ABC transporter, periplasmic zinc-binding protein; COG4531 ABC-type Zn2+ transport system, periplasmic component/surface adhesin.
  
  
 0.494
Your Current Organism:
Bermanella marisrubri
NCBI taxonomy Id: 207949
Other names: B. marisrubri, Bermanella marisrubri Pinhassi et al. 2009, CCUG 52064, CECT 7074, Oceanobacter sp. RED65, strain RED65
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.