node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAT10679.1 | EAT12696.1 | RED65_08584 | RED65_13467 | Probable acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase. | COG2867 Oligoketide cyclase/lipid transport protein. | 0.438 |
EAT11413.1 | EAT12696.1 | RED65_05837 | RED65_13467 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | COG2867 Oligoketide cyclase/lipid transport protein. | 0.607 |
EAT11413.1 | UbiH | RED65_05837 | RED65_05832 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.827 |
EAT11413.1 | ubiA | RED65_05837 | RED65_15282 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.746 |
EAT11413.1 | ubiB | RED65_05837 | RED65_16008 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.537 |
EAT11413.1 | ubiG | RED65_05837 | RED65_00095 | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.977 |
EAT12695.1 | EAT12696.1 | RED65_13462 | RED65_13467 | COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | COG2867 Oligoketide cyclase/lipid transport protein. | 0.617 |
EAT12695.1 | EAT12697.1 | RED65_13462 | RED65_13472 | COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family. | 0.640 |
EAT12695.1 | smpB | RED65_13462 | RED65_13457 | COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.610 |
EAT12696.1 | EAT10679.1 | RED65_13467 | RED65_08584 | COG2867 Oligoketide cyclase/lipid transport protein. | Probable acyltransferase; COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase. | 0.438 |
EAT12696.1 | EAT11413.1 | RED65_13467 | RED65_05837 | COG2867 Oligoketide cyclase/lipid transport protein. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.607 |
EAT12696.1 | EAT12695.1 | RED65_13467 | RED65_13462 | COG2867 Oligoketide cyclase/lipid transport protein. | COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.617 |
EAT12696.1 | EAT12697.1 | RED65_13467 | RED65_13472 | COG2867 Oligoketide cyclase/lipid transport protein. | COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family. | 0.915 |
EAT12696.1 | UbiH | RED65_13467 | RED65_05832 | COG2867 Oligoketide cyclase/lipid transport protein. | COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases. | 0.551 |
EAT12696.1 | dnaQ | RED65_13467 | RED65_04495 | COG2867 Oligoketide cyclase/lipid transport protein. | DNA polymerase III, epsilon subunit; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. | 0.449 |
EAT12696.1 | smpB | RED65_13467 | RED65_13457 | COG2867 Oligoketide cyclase/lipid transport protein. | SsrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.525 |
EAT12696.1 | ubiA | RED65_13467 | RED65_15282 | COG2867 Oligoketide cyclase/lipid transport protein. | 4-hydroxybenzoate polyprenyl transferase; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.441 |
EAT12696.1 | ubiB | RED65_13467 | RED65_16008 | COG2867 Oligoketide cyclase/lipid transport protein. | 2-polyprenylphenol 6-hydroxylase; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. | 0.451 |
EAT12696.1 | ubiG | RED65_13467 | RED65_00095 | COG2867 Oligoketide cyclase/lipid transport protein. | 3-demethylubiquinone-9 3-methyltransferase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. | 0.443 |
EAT12697.1 | EAT12695.1 | RED65_13472 | RED65_13462 | COG2914 Uncharacterized protein conserved in bacteria; Belongs to the UPF0125 (RnfH) family. | COG0733 Na+-dependent transporters of the SNF family; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. | 0.640 |