STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAT12284.14-carboxymuconolactone decarboxylase; COG0599 Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit. (122 aa)    
Predicted Functional Partners:
EAT12648.1
Hydrolase, alpha/beta fold family protein; COG0596 Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily).
  
 
 0.906
coaX
Transcriptional activator, putative, Baf family protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
       0.674
birA
Biotin--protein ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
       0.674
EAT12281.1
Hypothetical protein; COG1855 ATPase (PilT family).
       0.623
EAT11570.1
6-phosphogluconate dehydrogenase, NAD-binding protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
  
 0.572
EAT13612.1
Putative oxidoreductase protein; COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases.
  
  
 0.572
PurB
COG0015 Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.568
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
       0.548
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine.
       0.499
EAT12287.1
COG3242 Uncharacterized protein conserved in bacteria.
       0.492
Your Current Organism:
Bermanella marisrubri
NCBI taxonomy Id: 207949
Other names: B. marisrubri, Bermanella marisrubri Pinhassi et al. 2009, CCUG 52064, CECT 7074, Oceanobacter sp. RED65, strain RED65
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