STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EAR59970.1COG0518 GMP synthase - Glutamine amidotransferase domain. (232 aa)    
Predicted Functional Partners:
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
 0.873
EAR62968.1
Signaling protein (EAL,CBS,GGDEF domains); COG2200 FOG: EAL domain.
  
 
 0.800
EAR61683.1
COG0503 Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins.
  
 
 0.792
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
 
  
 0.744
EAR61190.1
COG0194 Guanylate kinase.
  
 
 0.734
surE
Acid phosphatase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.730
guaA
Bifunctional GMP synthase/glutamine amidotransferase protein; Catalyzes the synthesis of GMP from XMP.
    
 0.718
EAR60220.1
Phosphoserine phosphatase SerB:HAD-superfamily hydrolase, subfamily IB (PSPase-like); COG3830 ACT domain-containing protein.
    
  0.717
EAR62872.1
COG0127 Xanthosine triphosphate pyrophosphatase.
  
 
 0.713
EAR60691.1
Sulfur oxidation protein SoxB; COG0737 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases.
     
 0.704
Your Current Organism:
Neptuniibacter caesariensis
NCBI taxonomy Id: 207954
Other names: CCUG 52065, CECT 7075, N. caesariensis, Neptuniibacter caesariensis Arahal et al. 2007, Oceanospirillum sp. MED92, strain MED92
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