node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EAR59765.1 | EAR60108.1 | MED92_17625 | MED92_17252 | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | Ribose-phosphate pyrophosphokinase (RPPK)(Phosphoribosylpyrophosphate synthetase) (P-Rib-PP); COG0462 Phosphoribosylpyrophosphate synthetase. | 0.507 |
EAR59765.1 | glmS | MED92_17625 | MED92_05503 | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | Glucosamine--fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. | 0.920 |
EAR59765.1 | glmU | MED92_17625 | MED92_05508 | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase(N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.995 |
EAR59765.1 | murA | MED92_17625 | MED92_01649 | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.712 |
EAR59765.1 | murC | MED92_17625 | MED92_15815 | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | UDP-N-acetylmuramate--alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.819 |
EAR59765.1 | murE | MED92_17625 | MED92_15845 | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | UDP-N-acetylmuramoylalanyl-D-glutamate-2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.417 |
EAR60108.1 | EAR59765.1 | MED92_17252 | MED92_17625 | Ribose-phosphate pyrophosphokinase (RPPK)(Phosphoribosylpyrophosphate synthetase) (P-Rib-PP); COG0462 Phosphoribosylpyrophosphate synthetase. | Phosphoglucomutase protein MrsA; COG1109 Phosphomannomutase. | 0.507 |
EAR60108.1 | glmU | MED92_17252 | MED92_05508 | Ribose-phosphate pyrophosphokinase (RPPK)(Phosphoribosylpyrophosphate synthetase) (P-Rib-PP); COG0462 Phosphoribosylpyrophosphate synthetase. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase(N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.975 |
EAR60521.1 | EAR60528.1 | MED92_16695 | MED92_16730 | COG0381 UDP-N-acetylglucosamine 2-epimerase. | Probable UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | 0.998 |
EAR60521.1 | EAR63052.1 | MED92_16695 | MED92_08031 | COG0381 UDP-N-acetylglucosamine 2-epimerase. | COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase. | 0.812 |
EAR60521.1 | glmU | MED92_16695 | MED92_05508 | COG0381 UDP-N-acetylglucosamine 2-epimerase. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase(N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.920 |
EAR60521.1 | murA | MED92_16695 | MED92_01649 | COG0381 UDP-N-acetylglucosamine 2-epimerase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.877 |
EAR60528.1 | EAR60521.1 | MED92_16730 | MED92_16695 | Probable UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | COG0381 UDP-N-acetylglucosamine 2-epimerase. | 0.998 |
EAR60528.1 | EAR63052.1 | MED92_16730 | MED92_08031 | Probable UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase. | 0.823 |
EAR60528.1 | glmU | MED92_16730 | MED92_05508 | Probable UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase(N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.896 |
EAR60528.1 | murA | MED92_16730 | MED92_01649 | Probable UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.876 |
EAR60873.1 | glmU | MED92_16540 | MED92_05508 | Hypothetical protein; COG3178 Predicted phosphotransferase related to Ser/Thr protein kinases. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase(N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.916 |
EAR63052.1 | EAR60521.1 | MED92_08031 | MED92_16695 | COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase. | COG0381 UDP-N-acetylglucosamine 2-epimerase. | 0.812 |
EAR63052.1 | EAR60528.1 | MED92_08031 | MED92_16730 | COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase. | Probable UDP-glucose/GDP-mannose dehydrogenase; COG0677 UDP-N-acetyl-D-mannosaminuronate dehydrogenase. | 0.823 |
EAR63052.1 | glmU | MED92_08031 | MED92_05508 | COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase. | Bifunctional: N-acetyl glucosamine-1-phosphate uridyltransferase(N-terminal); Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. | 0.924 |