STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
nfuAyhgI protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. (197 aa)    
Predicted Functional Partners:
iscS
COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes.
  
 
 0.985
EAR59654.1
FeS cluster assembly scaffold IscU; COG0822 NifU homolog involved in Fe-S cluster formation.
  
 
 0.977
sdhB
COG0479 Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit.
  
 
 0.930
EAR61860.1
Nitrite reductase [NAD(P)H] large subunit; COG1251 NAD(P)H-nitrite reductase.
  
 0.914
EAR62073.1
Iron-sulfur cluster-binding protein; COG1145 Ferredoxin.
  
  
 0.913
hscB
Co-chaperone HscB; COG1076 DnaJ-domain-containing proteins 1.
  
 
 0.909
djlA
Dna-J like membrane chaperone protein; COG1076 DnaJ-domain-containing proteins 1.
  
 
 0.909
EAR62752.1
4Fe-4S ferredoxin, iron-sulfur binding; COG1145 Ferredoxin.
  
  
 0.906
grxD
COG0278 Glutaredoxin-related protein; Belongs to the glutaredoxin family. Monothiol subfamily.
  
 0.902
EAR61869.1
Molybdopterin oxidoreductase; COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing.
    
 0.858
Your Current Organism:
Neptuniibacter caesariensis
NCBI taxonomy Id: 207954
Other names: CCUG 52065, CECT 7075, N. caesariensis, Neptuniibacter caesariensis Arahal et al. 2007, Oceanospirillum sp. MED92, strain MED92
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