Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
fhuFHydroxamate siderophore iron reductase FhuF; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)    
Predicted Functional Partners:
tonB
TonB system transport protein TonB; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
 
    0.919
APZ06538.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.917
exbB
tonB-system energizer ExbB; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.902
exbD
Biopolymer transport protein ExbD; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.879
fhuA
Ferrichrome porin FhuA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.849
APZ04034.1
TonB-dependent siderophore receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.799
APZ07515.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.730
APZ04010.1
Phosphoglycerol transferase I; Catalyzes the transfer of phosphoglycerol to the glucan backbone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.702
APZ06681.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.699
APZ07311.1
Multidrug ABC transporter permease/ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.680
Your Current Organism:
Kosakonia cowanii
NCBI taxonomy Id: 208223
Other names: CCUG 45998 A, CCUG 45998 B, CIP 107300, DSM 18146, Enterobacter cowanii, Enterobacter cowanii Inoue et al. 2001, JCM 10956, K. cowanii, Kosakonia cowanii (Inoue et al. 2001) Brady et al. 2013, LMG 23569, LMG:23569, NIH group 42, strain 888-76, strain KSK 246, strain UM-79
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