Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
dnaTPrimosomal protein DnaI; This protein is required for primosome-dependent normal DNA replication; it is also involved in inducing stable DNA replication during SOS response. It forms, in concert with DnaB protein and other prepriming proteins DnaC, N, N', N'' a prepriming protein complex on the specific site of the template DNA recognized by protein N'. (179 aa)    
Predicted Functional Partners:
dnaC
DNA replication protein DnaC; Acts to load the DnaB helicase onto the initiation site during DNA replication; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
  0.878
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily.
    
 0.516
APZ06647.1
Helicase DnaB; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.516
APZ04007.1
Organic hydroperoxide resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.482
APZ04010.1
Phosphoglycerol transferase I; Catalyzes the transfer of phosphoglycerol to the glucan backbone; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.435
dnaG
DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
    
  0.432
Your Current Organism:
Kosakonia cowanii
NCBI taxonomy Id: 208223
Other names: CCUG 45998 A, CCUG 45998 B, CIP 107300, DSM 18146, Enterobacter cowanii, Enterobacter cowanii Inoue et al. 2001, JCM 10956, K. cowanii, Kosakonia cowanii (Inoue et al. 2001) Brady et al. 2013, LMG 23569, LMG:23569, NIH group 42, strain 888-76, strain KSK 246, strain UM-79
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