STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
treFAlpha,alpha-trehalase; Hydrolyzes trehalose to glucose. Could be involved, in cells returning to low osmolarity conditions, in the utilization of the accumulated cytoplasmic trehalose, which was synthesized in response to high osmolarity. (559 aa)    
Predicted Functional Partners:
APZ07039.1
Trehalose-phosphatase; Removes the phosphate from trehalose 6-phosphate to produce free trehalose.
 
 0.990
treZ
Malto-oligosyltrehalose trehalohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.939
treA
Alpha,alpha-trehalase; Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system; Belongs to the glycosyl hydrolase 37 family.
  
  
 
0.906
APZ03640.1
6-phospho-alpha-glucosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.900
APZ06277.1
Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide.
   
  
 0.649
APZ07678.1
Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family.
   
  
 0.649
APZ05764.1
Phosphoglucomutase, alpha-D-glucose phosphate-specific; Catalyzes the interconversion of alpha-D-glucose 1-phosphate to alpha-D-glucose 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.576
glk
Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family.
    
 0.519
galM
Galactose-1-epimerase; Converts alpha-aldose to the beta-anomer.
   
 
  0.501
APZ07038.1
Alpha,alpha-trehalose-phosphate synthase; Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family.
 
  
 0.490
Your Current Organism:
Kosakonia cowanii
NCBI taxonomy Id: 208223
Other names: CCUG 45998 A, CCUG 45998 B, CIP 107300, DSM 18146, Enterobacter cowanii, Enterobacter cowanii Inoue et al. 2001, JCM 10956, K. cowanii, Kosakonia cowanii (Inoue et al. 2001) Brady et al. 2013, LMG 23569, LMG:23569, NIH group 42, strain 888-76, strain KSK 246, strain UM-79
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