STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pqqCPyrroloquinoline quinone biosynthesis protein C; Ring cyclization and eight-electron oxidation of 3a-(2-amino- 2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline-7,9- dicarboxylic-acid to PQQ. (251 aa)    
Predicted Functional Partners:
pqqB
Pyrroloquinoline quinone biosynthesis protein B; May be involved in the transport of PQQ or its precursor to the periplasm; Belongs to the PqqB family.
  
 0.998
pqqD
Pyrroloquinoline quinone biosynthesis protein PqqD; Functions as a PqqA binding protein and presents PqqA to PqqE, in the pyrroloquinoline quinone (PQQ) biosynthetic pathway.
 
  
 0.995
pqqE
Pyrroloquinoline quinone biosynthesis protein PqqE; Catalyzes the cross-linking of a glutamate residue and a tyrosine residue in the PqqA protein as part of the biosynthesis of pyrroloquinoline quinone (PQQ).
 
  
 0.988
pqqF
Coenzyme PQQ biosynthesis protein PqqF; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M16 family.
 
   
 0.891
APZ03868.1
Membrane-bound PQQ-dependent dehydrogenase, glucose/quinate/shikimate family; Quinoprotein glucose dehydrogenase; catalyzes the formation of D-glucono-1,5-lactone from D-glucose and ubiquinone; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.683
APZ05186.1
Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.618
pqqA
Coenzyme PQQ precursor peptide PqqA; Required for coenzyme pyrroloquinoline quinone (PQQ) biosynthesis. PQQ is probably formed by cross-linking a specific glutamate to a specific tyrosine residue and excising these residues from the peptide; Belongs to the PqqA family.
       0.603
BWI95_07460
Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.533
APZ07436.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.530
moaA
Hypothetical protein; Molybdenum cofactor riboswitch; Derived by automated computational analysis using gene prediction method: cmsearch.
   
  
 0.524
Your Current Organism:
Kosakonia cowanii
NCBI taxonomy Id: 208223
Other names: CCUG 45998 A, CCUG 45998 B, CIP 107300, DSM 18146, Enterobacter cowanii, Enterobacter cowanii Inoue et al. 2001, JCM 10956, K. cowanii, Kosakonia cowanii (Inoue et al. 2001) Brady et al. 2013, LMG 23569, LMG:23569, NIH group 42, strain 888-76, strain KSK 246, strain UM-79
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