Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Gene Fusion
Co-occurrence
Co-expression
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[Homology]
Score
lacYMFS transporter; Lactose/proton symporter; mediates lactose/proton symport through the membrane by utilizing the proton gradient to drive transport of galactosides; member of major facilitator superfamily; functions as a monomer with 12 transmembrane segments; Derived by automated computational analysis using gene prediction method: Protein Homology. (421 aa)    
Predicted Functional Partners:
APZ07117.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
APZ06734.1
Nitrate reductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
  
 0.700
APZ03883.1
alpha-N-arabinofuranosidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 43 family.
 
  
 0.657
narJ
Nitrate reductase molybdenum cofactor assembly chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.613
narH
Nitrate reductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.605
BWI95_18600
Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.575
narI
Respiratory nitrate reductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.566
APZ05598.1
Maltose O-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.561
APZ07118.1
LacI family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.560
cobA-2
uroporphyrinogen-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.495
Your Current Organism:
Kosakonia cowanii
NCBI taxonomy Id: 208223
Other names: CCUG 45998 A, CCUG 45998 B, CIP 107300, DSM 18146, Enterobacter cowanii, Enterobacter cowanii Inoue et al. 2001, JCM 10956, K. cowanii, Kosakonia cowanii (Inoue et al. 2001) Brady et al. 2013, LMG 23569, LMG:23569, NIH group 42, strain 888-76, strain KSK 246, strain UM-79
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