Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
APZ07196.1Tyrosine-protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (722 aa)    
Predicted Functional Partners:
APZ07198.1
Polysaccharide export protein Wza; Required for the translocation of capsular polysaccharide through the outer membrane; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.989
APZ07197.1
Protein tyrosine phosphatase; Wzb shows phosphatase activity towards the autophosphorylated Wzc protein, which induces colanic acid biosynthesis; catalyzes the phosphorylation of UDP-glucose dehydrogenase, an enzyme involved in colanic acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the low molecular weight phosphotyrosine protein phosphatase family.
 
 
 0.959
nuoC
NADH-quinone oxidoreductase subunit C/D; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; In the C-terminal section; belongs to the complex I 49 kDa subunit family.
     
 0.836
APZ07184.1
Undecaprenyl-phosphate glucose phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.796
APZ07185.1
Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mannose-6-phosphate isomerase type 2 family.
 
  
 0.717
hypA
Hydrogenase maturation nickel metallochaperone HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
   
   0.701
wcaC
Colanic acid biosynthesis glycosyltransferase WcaC; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.697
wcaI
Colanic acid biosynthesis glycosyltransferase WcaI; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.693
wcaE
Colanic acid biosynthesis glycosyltransferase WcaE; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.687
wcaA
Colanic acid biosynthesis glycosyltransferase WcaA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.665
Your Current Organism:
Kosakonia cowanii
NCBI taxonomy Id: 208223
Other names: CCUG 45998 A, CCUG 45998 B, CIP 107300, DSM 18146, Enterobacter cowanii, Enterobacter cowanii Inoue et al. 2001, JCM 10956, K. cowanii, Kosakonia cowanii (Inoue et al. 2001) Brady et al. 2013, LMG 23569, LMG:23569, NIH group 42, strain 888-76, strain KSK 246, strain UM-79
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