| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SAG0787 | SAG1574 | SAG0787 | SAG1574 | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | DNA polymerase III, delta prime subunit, putative. | 0.999 |
| SAG0787 | dnaE | SAG0787 | SAG0939 | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | DNA polymerase III, alpha subunit; Identified by match to PFAM protein family HMM PF01336. | 0.999 |
| SAG0787 | dnaN | SAG0787 | SAG0002 | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.999 |
| SAG0787 | dnaX | SAG0787 | SAG0828 | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.999 |
| SAG0787 | hexB | SAG0787 | SAG2098 | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | DNA mismatch repair protein HexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.648 |
| SAG0787 | polA | SAG0787 | SAG0389 | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.565 |
| SAG1574 | SAG0787 | SAG1574 | SAG0787 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase III, delta subunit, putative; Similar to GP:2765186; identified by sequence similarity; putative. | 0.999 |
| SAG1574 | dinP | SAG1574 | SAG1726 | DNA polymerase III, delta prime subunit, putative. | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.729 |
| SAG1574 | dnaE | SAG1574 | SAG0939 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase III, alpha subunit; Identified by match to PFAM protein family HMM PF01336. | 0.999 |
| SAG1574 | dnaN | SAG1574 | SAG0002 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
| SAG1574 | dnaX | SAG1574 | SAG0828 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.999 |
| SAG1574 | hexB | SAG1574 | SAG2098 | DNA polymerase III, delta prime subunit, putative. | DNA mismatch repair protein HexB; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.604 |
| SAG1574 | polA | SAG1574 | SAG0389 | DNA polymerase III, delta prime subunit, putative. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.957 |
| dinP | SAG1574 | SAG1726 | SAG1574 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, delta prime subunit, putative. | 0.729 |
| dinP | dnaE | SAG1726 | SAG0939 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, alpha subunit; Identified by match to PFAM protein family HMM PF01336. | 0.536 |
| dinP | dnaN | SAG1726 | SAG0002 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.987 |
| dinP | hexA | SAG1726 | SAG2101 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA mismatch repair protein HexA; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.417 |
| dinP | polA | SAG1726 | SAG0389 | DNA-damage-inducible protein P; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity. | 0.832 |
| dnaA | dnaE | SAG0001 | SAG0939 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, alpha subunit; Identified by match to PFAM protein family HMM PF01336. | 0.801 |
| dnaA | dnaN | SAG0001 | SAG0002 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.998 |
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