Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAG0010S4 domain protein; Identified by match to PFAM protein family HMM PF01479. (90 aa)    
Predicted Functional Partners:
pavA
Adherence and virulence protein A; Similar to OMNI:SP0966; identified by sequence similarity; putative.
  
 
 
 0.936
rplS
Ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.
  
   0.887
SAG0011
Cell division protein DivIC, putative; Similar to OMNI:NTL01SPL0011; identified by sequence similarity; putative.
  
    0.845
rplQ
Ribosomal protein L17; Identified by match to PFAM protein family HMM PF01196.
   
 
 0.845
rpmB
Ribosomal protein L28; Identified by match to PFAM protein family HMM PF00830; Belongs to the bacterial ribosomal protein bL28 family.
  
   0.839
rpmH
Ribosomal protein L34; Identified by match to PFAM protein family HMM PF00468; Belongs to the bacterial ribosomal protein bL34 family.
   
   0.835
rplB
Ribosomal protein L2; One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome. Belongs to the universal ribosomal protein uL2 family.
    
 
 0.829
rpmA
Ribosomal protein L27; Identified by match to PFAM protein family HMM PF01016; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.829
rplT
Ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
   0.829
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
    
   0.825
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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