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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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purEPhosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (162 aa)    
Predicted Functional Partners:
purC
Phosphoribosylaminoimidazole-succinocarboxamide synthase; Identified by match to PFAM protein family HMM PF01259; Belongs to the SAICAR synthetase family.
 
 0.999
SAG0025
Phosphoribosylformylglycinamidine synthase, putative; Identified by match to PFAM protein family HMM PF02769.
 
 
 0.999
purD
Phosphoribosylamine--glycine ligase; Identified by match to PFAM protein family HMM PF01071; Belongs to the GARS family.
 0.999
purK
Phosphoribosylaminoimidazole carboxylase, ATPase subunit; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).
 0.999
purB
Adenylosuccinate lyase; Identified by match to PFAM protein family HMM PF00206; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 0.999
purM
Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to PFAM protein family HMM PF00586.
 
 
 0.997
purN
Phosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.
 
 
 0.997
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.996
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Identified by match to PFAM protein family HMM PF01808.
 
  
 0.991
purA
Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.981
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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