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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
truAtRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (258 aa)    
Predicted Functional Partners:
SAG0101
Phosphomethylpyrimidine kinase, putative; Identified by match to PFAM protein family HMM PF00294.
  
    0.863
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
  
 0.842
rsmH
Conserved hypothetical protein TIGR00006; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.
   
 
 0.791
SAG0102
Conserved hypothetical protein; Identified by Glimmer2; putative.
       0.790
SAG0103
Conserved hypothetical protein TIGR01440; Identified by Glimmer2; putative; Belongs to the UPF0340 family.
       0.790
trmE
tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.
 
  
 0.789
rplQ
Ribosomal protein L17; Identified by match to PFAM protein family HMM PF01196.
  
  
 0.768
SAG0522
Metallo-beta-lactamase superfamily protein; Identified by match to PFAM protein family HMM PF00753.
   
 
 0.762
ybeY
Conserved hypothetical protein TIGR00043; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
   
   0.759
SAG0472
Rhodanese-like domain protein; Identified by match to PFAM protein family HMM PF00581; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.
 
 
 
 0.742
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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