Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SAG0103Conserved hypothetical protein TIGR01440; Identified by Glimmer2; putative; Belongs to the UPF0340 family. (189 aa)    
Predicted Functional Partners:
SAG0102
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
    0.932
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.
       0.833
SAG0101
Phosphomethylpyrimidine kinase, putative; Identified by match to PFAM protein family HMM PF00294.
       0.777
prmC
Modification methylase, HemK family; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.
      0.712
lacB
Galactose-6-phosphate isomerase, LacB subunit; Identified by match to PFAM protein family HMM PF02502.
  
    0.660
lacA
Galactose-6-phosphate isomerase, LacA subunit; Identified by match to PFAM protein family HMM PF02502.
  
    0.660
SAG0099
Transcriptional regulator, GntR family; Identified by match to PFAM protein family HMM PF00392.
       0.568
dnaJ
dnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...]
       0.563
SAG1905
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
    0.554
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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