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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SAG0146Penicillin-binding protein 4, putative; Identified by match to PFAM protein family HMM PF00768; Belongs to the peptidase S11 family. (395 aa)    
Predicted Functional Partners:
SAG0147
Identified by match to PFAM protein family HMM PF00768; Belongs to the peptidase S11 family.
 
    
0.651
SAG0765
Penicillin-binding protein 2b; Identified by match to PFAM protein family HMM PF00905.
  
 
 0.564
SAG0319
Serine/threonine protein kinase; Identified by match to PFAM protein family HMM PF00069.
  
 
 0.556
pbpX
Penicillin-binding protein 2X; Identified by match to PFAM protein family HMM PF00905.
  
 
 0.541
SAG0013
Protein of unknown function; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.
 
  
  0.509
SAG0093
Identified by match to PFAM protein family HMM PF02557.
    
 0.463
SAG0159
Penicillin-binding protein 1B, putative; Identified by match to PFAM protein family HMM PF00905.
  
 
 0.463
SAG0755
Peptidase, U32 family; Similar to OMNI:NTL01SPL0447; identified by sequence similarity; putative.
  
  
  0.432
greA
Transcription elongation factor GreA; Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.
 
     0.426
pbp1A
Penicillin-binding protein 1A; Identified by match to PFAM protein family HMM PF00905.
  
 
 0.408
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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