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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflD-1Formate acetyltransferase; Identified by match to PFAM protein family HMM PF01228. (818 aa)    
Predicted Functional Partners:
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 
 0.928
pflA-1
Pyruvate formate-lyase-activating enzyme; Identified by match to PFAM protein family HMM PF02143.
 
  
 0.913
SAG0332
Identified by match to PFAM protein family HMM PF00923.
 
  
 0.901
SAG0881
Acetoin dehydrogenase, thymine PPi dependent, E3 component, dihydrolipoamide dehydrogenase; Identified by match to PFAM protein family HMM PF00070.
   
 
 0.862
SAG1092
Phosphate acetyltransferase; Identified by match to PFAM protein family HMM PF01515.
  
 
 0.836
pflA-2
Pyruvate formate-lyase-activating enzyme; Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine; Belongs to the organic radical-activating enzymes family.
 
  
 0.816
SAG0326
Transcriptional regulator, DeoR family; Identified by match to PFAM protein family HMM PF00455.
 
 
 0.720
SAG0879
Acetoin dehydrogenase, thymine PPi dependent, E1 component, beta subunit; Identified by match to PFAM protein family HMM PF02779.
   
 
 0.703
SAG0878
Acetoin dehydrogenase, thymine PPi dependent, E1 component, alpha subunit; Identified by match to PFAM protein family HMM PF00676.
   
 
 0.685
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family.
   
 
 0.679
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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