Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SAG0429Oxidoreductase, aldo/keto reductase family; Identified by match to PFAM protein family HMM PF00248. (284 aa)    
Predicted Functional Partners:
adhE
Aldehyde-alcohol dehydrogenase; Identified by match to PFAM protein family HMM PF00171; In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.
  
 0.836
gloA
Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione.
   
 0.752
SAG1541
Glyoxalase family protein.
   
 0.752
SAG0428
Alcohol dehydrogenase, zinc-containing; Identified by match to PFAM protein family HMM PF00107.
  
 0.739
SAG1806
Glyoxylate reductase, NADH-dependent; Identified by match to PFAM protein family HMM PF00389; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.695
sdhB
L-serine dehydratase, iron-sulfur-dependent, beta subunit; Identified by match to PFAM protein family HMM PF01842; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.655
sdhA
L-serine dehydratase, iron-sulfur-dependent, alpha subunit; Identified by match to PFAM protein family HMM PF03313; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
  0.655
SAG0427
Transcriptional regulator, MerR family; Identified by match to PFAM protein family HMM PF00376.
      0.598
SAG0426
Conserved hypothetical protein; Identified by Glimmer2; putative.
 
     0.596
SAG0430
Cation efflux system protein; Identified by match to PFAM protein family HMM PF01545.
  
    0.563
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
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