Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
SAG0502DegV family protein; Identified by match to PFAM protein family HMM PF02645; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. (278 aa)    
Predicted Functional Partners:
SAG0131
DAK2 domain protein; Identified by match to PFAM protein family HMM PF02734.
 
 0.995
SAG0504
Conserved hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.866
SAG0503
Lipase/acylhydrolase; Identified by match to PFAM protein family HMM PF00657; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002.
     
 0.854
hup
DNA-binding protein HU; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions.
     
 0.712
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
       0.669
xseA
Exodeoxyribonuclease VII, large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family.
       0.661
xseB
Exodeoxyribonuclease VII, small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family.
       0.661
SAG0498
Geranyltranstransferase, putative; Identified by match to PFAM protein family HMM PF00348; Belongs to the FPP/GGPP synthase family.
       0.661
SAG0499
Identified by match to PFAM protein family HMM PF01479.
       0.661
argR
Arginine repressor ArgR, putative; Regulates arginine biosynthesis genes.
       0.661
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: low (14%) [HD]