Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
fbpFructose-1,6-bisphosphatase, putative; Similar to PID:1064791 GB:AL009126; identified by sequence similarity; putative. (643 aa)    
Predicted Functional Partners:
pgi
Glucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342.
  
  
 0.942
fba
Fructose-bisphosphate aldolase; Identified by match to PFAM protein family HMM PF01116.
 
  
 0.940
pfk
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
     
 0.933
fruK
1-phosphofructokinase; Identified by match to PFAM protein family HMM PF00294; Belongs to the carbohydrate kinase PfkB family. LacC subfamily.
    
 0.911
manA
Mannose-6-phosphate isomerase, class I; Identified by match to PFAM protein family HMM PF01238; Belongs to the mannose-6-phosphate isomerase type 1 family.
     
 0.908
scrK
Fructokinase; Identified by match to PFAM protein family HMM PF00480.
     
 0.906
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
     
  0.904
SAG0332
Identified by match to PFAM protein family HMM PF00923.
     
  0.904
tal
Transaldolase family protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily.
     
  0.904
SAG0199
Transketolase, N-terminal subunit; Identified by match to PFAM protein family HMM PF00456.
     
  0.866
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.