Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (435 aa)    
Predicted Functional Partners:
pgk
Phosphoglycerate kinase; Identified by match to PFAM protein family HMM PF00162; Belongs to the phosphoglycerate kinase family.
 
 
 0.996
pgi
Glucose-6-phosphate isomerase; Identified by match to PFAM protein family HMM PF00342.
  
 0.995
pyk
Pyruvate kinase; Identified by match to PFAM protein family HMM PF00224; Belongs to the pyruvate kinase family.
 
 0.993
fba
Fructose-bisphosphate aldolase; Identified by match to PFAM protein family HMM PF01116.
  
 0.992
tpiA
Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 
 0.990
gap
Glyceraldehyde 3-phosphate dehydrogenase; Identified by match to PFAM protein family HMM PF00044; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 0.990
gpmA
Phosphoglycerate mutase family protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate.
  
 0.987
tkt
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.981
gapN
Glyceraldehyde-3-phosphate dehydrogenase, NADP-dependent; Identified by match to PFAM protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
 0.956
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
   
   0.955
Your Current Organism:
Streptococcus agalactiae
NCBI taxonomy Id: 208435
Other names: S. agalactiae 2603V/R, Streptococcus agalactiae 2603V/R, Streptococcus agalactiae str. 2603V/R
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.