| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| SAG0368 | SAG0632 | SAG0368 | SAG0632 | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | 0.784 |
| SAG0368 | codY | SAG0368 | SAG1675 | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | Transcriptional regulator CodY, putative; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.482 |
| SAG0368 | dltA | SAG0368 | SAG1790 | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...] | 0.696 |
| SAG0368 | dltB | SAG0368 | SAG1789 | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | dltB protein; Could be involved in the transport of activated D-alanine through the membrane. | 0.697 |
| SAG0368 | dltC | SAG0368 | SAG1788 | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.693 |
| SAG0368 | dltD | SAG0368 | SAG1787 | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | dltD protein; Similar to OMNI:SP2173; identified by sequence similarity; putative. | 0.693 |
| SAG0632 | SAG0368 | SAG0632 | SAG0368 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | Protein of unknown function; Identified by match to TIGR protein family HMM TIGR00350; The product of this gene was detected by Western blot analysis. For details on the method see Tettelin et al. 2002. | 0.784 |
| SAG0632 | aroA | SAG0632 | SAG0630 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.726 |
| SAG0632 | aroK | SAG0632 | SAG0631 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.742 |
| SAG0632 | codY | SAG0632 | SAG1675 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | Transcriptional regulator CodY, putative; DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor; Belongs to the CodY family. | 0.670 |
| SAG0632 | cpsA | SAG0632 | SAG1175 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | Capsular polysaccharide biosynthesis protein CpsA; Identified by match to TIGR protein family HMM TIGR00350. | 0.846 |
| SAG0632 | dltA | SAG0632 | SAG1790 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | D-alanine-activating enzyme; Catalyzes the first step in the D-alanylation of lipoteichoic acid (LTA), the activation of D-alanine and its transfer onto the D- alanyl carrier protein (Dcp) DltC. In an ATP-dependent two-step reaction, forms a high energy D-alanyl-AMP intermediate, followed by transfer of the D-alanyl residue as a thiol ester to the phosphopantheinyl prosthetic group of the Dcp. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. Belongs to the ATP-dependent AMP [...] | 0.905 |
| SAG0632 | dltB | SAG0632 | SAG1789 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | dltB protein; Could be involved in the transport of activated D-alanine through the membrane. | 0.905 |
| SAG0632 | dltC | SAG0632 | SAG1788 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | D-alanyl carrier protein; Carrier protein involved in the D-alanylation of lipoteichoic acid (LTA). The loading of thioester-linked D-alanine onto DltC is catalyzed by D-alanine--D-alanyl carrier protein ligase DltA. The DltC- carried D-alanyl group is further transferred to cell membrane phosphatidylglycerol (PG) by forming an ester bond, probably catalyzed by DltD. D-alanylation of LTA plays an important role in modulating the properties of the cell wall in Gram-positive bacteria, influencing the net charge of the cell wall. | 0.904 |
| SAG0632 | dltD | SAG0632 | SAG1787 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | dltD protein; Similar to OMNI:SP2173; identified by sequence similarity; putative. | 0.904 |
| SAG0632 | ftsW | SAG0632 | SAG0761 | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | Cell division protein, FtsW/RodA/SpoVE family; Identified by match to PFAM protein family HMM PF01098; Belongs to the SEDS family. | 0.581 |
| aroA | SAG0632 | SAG0630 | SAG0632 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | 0.726 |
| aroA | aroK | SAG0630 | SAG0631 | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.999 |
| aroK | SAG0632 | SAG0631 | SAG0632 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | Psr protein; Identified by match to TIGR protein family HMM TIGR00350. | 0.742 |
| aroK | aroA | SAG0631 | SAG0630 | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.999 |
